谢帝芝
姓名:谢帝芝
职务:水生动物营养与饲料科学系系主任
职称:副研究员
联系方式:
谢帝芝,博士,副研究员,硕士生导师,广东省动物学、海洋湖沼学、海洋学等学会理事,广东省科技特派员。主要从事水产动物营养与饲料等方面的科研和教学工作;近年来,已主持承担包括国家自然科学基金在内的科研课题11项,作为主要参与人,参加国家自然科学基金在内的科研课题14项,在鱼类脂肪酸精准营养需求及其品质调控等研究方面,取得了一系列成果,获广东省自然科学二等奖1项,授权发明专利3件,参编著作3部;在《Progress in Lipid Research》《Journal of Agricultural and Food Chemistry》《水产学报》等本领域重要期刊上发表论文90余篇(SCI论文60篇),担任《Frontiers in Marine Science》《Foods》《Life》客座编辑,以及《Review in Aquaculture》《Aquaculture》等国内外期刊审稿人。
工作经历
2017/06-至今, 华南农业大学,海洋学院;
2020/01-2021/01,新加坡国立大学理学院 访问学者;
2014/07-2017/06,河南师范大学,水产学院。
学习经历
2011/09-2014/06,汕头大学,海洋生物学,理学博士;
2008/09-2011/06,湖南农业大学,渔业资源,农业硕士;
2005/07-2008/06,湖南农业大学,生物工程,工学学士;
2004/09-2007/06,长沙学院,生物工程。
代表性学术成果:
一、主持或参加省部级以上的主要科研项目:
1) 国家自然科学基金青年科基金项目, 31602176, 鲤Acsl6在肌肉DHA沉积中的调控机制研究, 2017/01-2019/12, 主持;
2) 广东省基础与应用基础研究基金青年提升项目,2024A1515030246, Omega 3改善罗非鱼肌肉质地的调控机制研究, 2024.1-2026-12, 主持;
3) 广东省基础与应用基础研究基金面上项目, 2021A1515011123, 饲料脂肪酸组成提升罗非鱼肌肉品质的机制研究,2021.1-2023-12,主持;
4) 广东省科技专项, 210726116902191, 蓝子鱼高效环保配合饲料的研发及其推广应用, 2022.1-2023.12, 主持;
5) 广东省鳗鱼产业园项目, h2019289, 鳗鱼养殖环境与产品质量安全检测技术, 2019/01-2022/12, 结题, 主持;
6) 河南省高等学校重点科研项目, 15A240004, 高效脂肪模式在鲤养殖中的应用, 2015/01-2016/12, 结题, 主持;
7) 国家海水鱼产业技术体系岗位科学家项目, CARS-47-G13, 军曹鱼卵形鲳鲹营养需求与饲料, 2017.1-2021.12, 岗位秘书;
8) 国家重点研发计划“蓝色粮仓科技创新”重点专项“水产动物精准营养及其代谢调控机制”, 2018YFD0900400, 2018.12-2022.12, 第二参与人;
9) 国家自然科学基金面上项目, 32273148, 饲料脂肪酸组成通过Ampk/Srebp信号通路影响鱼类养殖性能的机制研究, 2023.1- 2026.12, 第二参与人;
10) 国家自然科学基金青年项目, 31702358, adiponectin/AdipoR对草鱼肝脏糖代谢的调控及机制研究, 2018.1-2021.12, 第二参与人;
11) 国家自然科学基金地区联合项目, U1704109, 草鱼脂肪肝细胞exosomes传递miR-122调节干细胞与免疫细胞间相互作用和机制研究, 2021.1-2023.12, 第三参与人;
12) 国家自然科学基金区域创新发展联合基金重点项目, U22A20532, 黄河鲤重要品质性状的形成机制与营养调控, 2023.1-2026.12, 第四参与人;
13) 国家自然科学基金面上项目, 31873040, 广盐性鱼类在不同盐度下的HUFA合成能力的影响机制研究, 2019.1-2022.12, 第四参与人;
14) 国家自然科学基金面上项目, 31672671, Apelin对鲤肠肝轴糖代谢的调控机制研究, 2017.1-2020.12, 第四参与人;
15) 广东省促进经济高质量发展专项资金海洋经济发展项目, GDOE【2019】A30号, 卵形鲳鲹高效低成本环保配合饲料的研发及其产业化应用, 2019.1- 2020.12, 第二参与人.
二、期刊论文(第一作者/通讯作者)
1) Xie D#, Chen C#, Dong Y#, et al. Regulation of long-chain polyunsaturated fatty acid biosynthesis in teleost fish. Progress in Lipid Research, 2021, 82: 101095.
2) Xie D#, Guan J#, Huang X, et al. Tilapia can be a beneficial n-3 LC-PUFA source due to its high biosynthetic capacity in the liver and intestine. Journal of Agricultural and Food Chemistry, 2022, 70(8): 2701-2711.
3) Chen F, He Y, Li X, et al. Improvement in muscle fatty acid bioavailability and volatile flavor in tilapia by dietary α-linolenic acid nutrition strategy. Foods, 2024, 13(7), 1005.(通讯作者)
4) Li, X., Gao, L., Chen, F. et al. Protein-sparing effects of lipids in the diet of golden pompano (Trachinotus ovatus): evaluation of growth, feed utilization, and lipid metabolism. Fish Physiol Biochem, 2024). https://doi.org/10.1007/s10695- 024-01392-9(通讯作者)
5) Huang X, Chen F, Sang Y, et al. Medium-short chain fatty acids cannot spare the essential fatty acids of low marine diets in golden pompano (Trachinotus ovatus). Aquaculture Reports, 2024. 36, 102126.(通讯作者)
6) Chen F, Ding Z, Su Z, et al., Efficiently substituting dietary fish meal with terrestrial compound protein enhances growth, health, and protein synthesis in largemouth bass. Animals, 2024, 14(15), 2196.(通讯作者)
7) An W, Xu J, Chen F, et al. Effects of dietary n-3 LC-PUFA levels on the growth, immunity, and lipid metabolism of freshwater carnivorous teleost largemouth bass (Micropterus salmoides) juveniles. Aquaculture Reports, 2023, 32: 101704.(通讯作者)
8) Chen F, Huang X, Zhu H, et al. Molecular characterization and expression analysis of acyl-CoA synthetase 6 in golden pompano Trachinotus ovatus reveal its function in DHA enrichment. Aquaculture, 2022, 551, 737966.(通讯作者)
9) Huang X, Chen F, Guan J, et al. Beneficial effects of re-feeding high α-linolenic acid diets on the muscle quality, cold temperature and disease resistance of tilapia.Fish & Shellfish Immunology. 2022, 126, 303-310.(通讯作者)
10) Yang Z, Zhu H, Huang X, et al. Molecular characterization, tissue distribution profile, and nutritional regulation of acsl gene family in golden pompano (Trachinotus ovatus). International Journal of Molecular Sciences, 2022, 23(12), 6437.(通讯作者)
11) He Z#, Xu C#, Chen F, et al. Dietary DHA Enhanced the textural firmness of common Carp (Cyprinus carpio L.) fed plant-derived Diets through restraining FoxO1 pathways. Foods, 2022, 11(22), 3600.(通讯作者)
12) Xu C, Li X, Gao L, et al. Molecular characterization of thioredoxin-interacting protein (TXNIP) from Megalobrama amblycephala and its potential roles in high glucose-induced inflammatory response. International Journal of Biological Macromolecules, 2021, 188, 460-472.(通讯作者)
13) Xu C, Li Y, Liu W, et al. Interactions between dietary carbohydrate and thiamine: Implications on the growth performance and intestinal mitochondrial biogenesis and function of Megalobrama amblycephala. British Journal of Nutrition, 2021, 127(3): 321-334.(通讯作者)
14) Fan B#, Xie, D#, Li Y, et al. A single intronic single nucleotide polymorphism in splicing site of steroidogenic enzyme hsd17b1 is associated with phenotypic sex in oyster pompano, Trachinotus anak. Proceedings of the Royal Society B, 2021, 288(1963), 20212245.
15) Alfiko, Y#, Xie, D#, Astuti, R. T, et al. Insects as a feed ingredient for fish culture: status and trends. Aquaculture and Fisheries.2021, 7(2):166-178.
16) Xie D*, Dai Q, Xu C, et al. Dietary tributyrin modifies intestinal function by altering morphology, gene expression and microbiota profile in common carp (Cyprinus carpio) fed all-plant diets. Aquaculture Nutrition, 2021, 27(2): 439-453.
17) Xie D, He Z, Dong Y, et al. Molecular Cloning, Characterization, and expression regulation of acyl-CoA synthetase 6 gene and promoter in common carp Cyprinus carpio. International journal of molecular sciences, 2020, 21(13): 4736.
18) Xie D, Ye J, Lu M, et al. Comparsion of activities of fatty acyl desaturases and elongases among six teleosts with different feeding and ecological habits. Frontiers in Marine Science, 2020, 7: 117.
19) Xie D, Wang M, Wang S, et al. Fat powder can be a feasible lipid source in aquafeed for the carnivorous marine teleost golden pompano, Trachinotus ovatus. Aquaculture International, 2020, 28(3): 1153-1168.
20) Xie D,Li X, You C, et al. Supplementation of macroalgae together with non-starch polysaccharide-degrading enzymes in diets enhanced growth performance, innate immune indexes, and disease resistance against Vibrio parahaemolyticus in rabbitfish Siganus canaliculatus. Journal of Applied Phycology, 2019, 31(3): 2073-2083.
21) Xie D, Fu Z, Wang S, et al. Characteristics of the fads2 gene promoter in marine teleost Epinephelus coioides and role of Sp1-binding site in determining promoter activity. Scientific reports, 2018, 8(1): 1-9.
22) Xie D, Liu X, Wang S, et al. Effects of dietary LNA/LA ratios on growth performance, fatty acid composition and expression levels of elovl5, Δ4 fad and Δ6/Δ5 fad in the marine teleost Siganus canaliculatus. Aquaculture, 2018, 484: 309-316.
23) Xie D, Xu S, Wu Q, et al. Changes of visceral properties and digestive enzymes in the herbivorous marine teleost Siganus canaliculatus fed on different diets. Acta Oceanologica Sinica, 2018, 37(2): 85-93.
24) Xie D, Yang L, Yu R, et al. Effects of dietary carbohydrate and lipid levels on growth and hepatic lipid deposition of juvenile tilapia, Oreochromis niloticus. Aquaculture, 2017, 479: 696-703.
25) Xie D, Xu S, Wang S, et al. Cloning, tissue expression, and nutritional regulation of the α-amylase gene in the herbivorous marine teleost Siganus canaliculatus. Aquaculture, 2016, 454: 229-236.
26) Xie D, Chen F, Lin S, et al. Long-chain polyunsaturated fatty acid biosynthesis in the euryhaline herbivorous teleost Scatophagus argus: Functional characterization, tissue expression and nutritional regulation of two fatty acyl elongases. Comparative Biochemistry and Physiology B, 2016, 198: 37-45.
27) Xie D, Wang S, You C, et al. Characteristics of LC-PUFA biosynthesis in marine herbivorous teleost Siganus canaliculatus under different ambient salinities. Aquaculture Nutrition, 2015, 21(5): 541-551.
28) Xie D, Chen F, Lin S, et al. Cloning, functional characterization and nutritional regulation of Δ6 fatty acyl desaturase in the herbivorous euryhaline teleost Scatophagus argus. PLoS one, 2014, 9(3): e90200.
三、授权发明专利
1)谢帝芝,李远友,朱航波,黄小平,陈芳. 一种基于脂肪酸精准营养需求提升罗非鱼肌肉品质的复合脂肪源, 2023-08-22, 中国,ZL 2022 1 0570656.1;
2)Li Yuanyou, Ma Yongcai, Xie Dizhi, Xu Chao. Compound feed for young fish of Trachinotus ovatus capable of efficiently substituting fish meal by animal and plant compound protein. Republic of South Africa, 2023-01-25, ZA2023/00178;
3)Li Yuanyou, Xie Dizhi, Ma Yongcai, Zhuang Guangrong. Feed additive capable of effectively improving substitution ratio of fish meal in compound feed of Trachinotus ovatus. Republic of South Africa, 2023-01-25, ZA2023/00179.
四、专著出版