魏世娜
姓名:魏世娜
职务:-
职称:副研究员
联系方式:weisn@scau.edu.cn
个人简介:
魏世娜:女,河北衡水人,博士,副研究员。研究方向:海洋鱼类分子免疫学及功能基因组学。主持国家级、省部级等项目共计3项:包括国家自然科学基金1项、广东省自然科学基金1项,广东省水产经济动物病原生物学及流行病学重点实验室开放课题1项;参与科技部海洋863 项目1项、国家自然科学基金国际(地区)合作与交流项目1项。近年来发表SCI论文32篇,其中第一作者SCI论文4篇,共同通讯作者6篇,参与发表SCI论文22篇;第一作者发表中文核心期刊2篇;参与申请专利6项。
教育经历:
2010.09-2013.07 中国科学院南海海洋研究所 海洋生物学专业 博士
2007.09-2010.07 广东海洋大学 水产养殖专业 硕士
2002.09-2006.07 河北科技师范学院 水产养殖教育专业 学士
科研项目:
1、国家自然科学基金青年基金(41506176)石斑鱼半胱氨酸蛋白酶抑制剂B(Cystatin B)在虹彩病毒SGIV感染中的作用及机制研究,2016.01-2018.12,在研,主持。
2、广东省自然科学基金博士启动基金(2014A030310387)石斑鱼Cystatin C基因在虹彩病毒SGIV感染中的作用机制研究,2015.01-2018.01,在研,主持。
3、广东省水产经济动物病原生物学及流行病学重点实验室开放课题(GDOUKL1503)斜带石斑鱼新型模式识别受体NLR的克隆、功能和信号途径的研究,2015.07-2017.07,在研,主持。
4、国际(地区)合作与交流项目(31461163007)鱼类虹彩病毒新型疫苗研发和机制,2015.01-2017.12,在研,参与。
5、国家“863”计划(2012AA092201-2)斜带石斑鱼免疫/抗病相关功能基因研究,2012.01-2014.12,已结题,参与。
发表论文:
1. Wei S, Huang Y, Huang X, Qin Q*. Characterization of c-Jun from orange-spotted grouper, Epinephelus coioides involved in SGIV infection. Fish Shellfish Immunol. 2015; 43(1): 230-40. (第一作者)
2. Wei S, Huang Y, Huang X, Cai J, Wei J, Li P, Ouyang Z, Qin Q*. Molecular cloning and characterization of a new G-type lysozyme gene (Ec-lysG) in orange-spotted grouper, Epinephelus coioides. Dev Comp Immunol. 2014; 46(2): 401-12. (第一作者)
3. Wei S, Huang Y, Huang X, Cai J, Yan Y, Guo C, Qin Q*. Characterization of cathepsin B gene from orange-spotted grouper, Epinephelus coioides involved in SGIV infection. Fish Shellfish Immunol. 2014; 36(1): 194-205. (第一作者)
4. Wei S, Huang Y, Cai J, Huang X, Fu J, Qin Q*. Molecular cloning and characterization of c-type lysozyme gene in orange-spotted grouper, Epinephelus coioides. Fish Shellfish Immunol. 2012; 33(2): 186-96. (第一作者)
5. 魏世娜, 简纪常*, 吴灶和, 鲁义善, 闫秀英. 鱼类非特异性细胞毒性细胞(NCC)的研究进展.中国水产科学. 2010; 17(2): 374-380. (第一作者)
6. 魏世娜, 王蓓, 鲁义善, 吴灶和, 简纪常*. 红笛鲷NCCRP-1 基因原核表达条件的优化及纯化. 广东海洋大学学报. 2010; 30(6): 25-30. (第一作者)
7. Li P, Zhou L, Yu Y, Yang M, Ni S, Wei S*, Qin Q*. Characterization of DNA aptamers generated against the soft-shelled turtle iridovirus with antiviral effects. BMC Vet Res. 2015; 11: 245. (共同通讯作者)
8. Li P, Yang M, Ni S, Zhou L, Wang Z, Wei S*, Qin Q*. Complete mitochondrial genome sequence of the pelagic chaetognath, Sagitta pacifica. Mitochondrial DNA. 2015; 18:1-2. (共同通讯作者)
9. Li P, Zhou L, Ni S, Xu M, Yu Y, Cai J, Wei S*, Qin Q*. Establishment and characterization of a novel cell line from the brain of golden pompano (Trachinotus ovatus). In Vitro Cell Dev Biol Anim. 2016; 52(4):410-8. (共同通讯作者)
10. Li P, Zhou L, Wei J, Yu Y, Yang M, Wei S*, Qin Q*. Development and characterization of aptamer-based enzyme-linked apta-sorbent assay for the detection of Singapore grouper iridovirus infection. J Appl Microbiol. 2016; 121(3): 634-43. (共同通讯作者)
11. Zhou L, Li P, Yang M, Yu Y, Huang Y, Wei J, Wei S*, Qin Q*. Generation and characterization of novel DNA aptamers against coat protein of grouper nervous necrosis virus (GNNV) with antiviral activities and delivery potential in grouper cells. Antiviral Res. 2016; 129:104-14. (共同通讯作者)
12. Yu Y, Wei S, Wang Z, Huang X, Huang Y, Cai J, Li C, Qin Q*. Establishment of a new cell line from the snout tissue of golden pompano Trachinotus ovatus, and its application in virus susceptibility. J Fish Biol. 2016; 88(6):2251-62.
13. Li P, Wei S, Zhou L, Yang M, Yu Y, Wei J, Jiang G, Qin Q*. Selection and characterization of novel DNA aptamers specifically recognized by Singapore grouper iridovirus-infected fish cells. J Gen Virol. 2015; 96(11): 3348-59.
14. Cai J, Wei S, Wang B, Huang Y, Tang J, Lu Y, Wu Z, Jian J*. Cloning and expression analysis of nonspecific cytotoxic cell receptor 1 (Ls-NCCRP1) from red snapper (Lutjanus sanguineus). Mar Genomics. 2013; 11: 39-44.
15. Guo C, Huang Y, Wei S, Ou-yang Z, Yan Y, Huang X and Qin Q*. Establishment of a new cell line from the heart of giant grouper, Epinephelus lanceolatus (Bloch), and its application in toxicology and virus susceptibility. J Fish Dis. 2015; 38(2): 175-86.
16. Ji H, Wei J, Wei S, Yan Y, Huang Y, Huang X, Zhou S, Zhou Y, Qin Q*. Molecular cloning and expression of a C-type lectin-like protein from orange-spotted grouper Epinephelus coioides. J Fish Biol. 2014; 84(2): 436-47.
17. Li P, Yan Y, Wei S, Wei J, Gao R, Huang X, Huang Y, Jiang G, Qin Q*. Isolation and characterization of a new class of DNA aptamers specific binding to Singapore grouper iridovirus (SGIV) with antiviral activities. Virus Res. 2014; 188: 146-54.
18. Cai J, Huang Y, Wei S, Ouyang Z, Huang X, Qin Q*. Characterization of LPS-induced TNFα factor (LITAF) from orange-spotted grouper, Epinephelus coioides. Fish Shellfish Immunol. 2013; 35(6): 1858-66.
19. Cai J, Huang Y, Wei S, Huang X, Ye F, Fu J, Qin Q*. Characterization of p38 MAPKs from orange-spotted grouper, Epinephelus coioides involved in SGIV infection. Fish Shellfish Immunol. 2011; 31(6): 1129-36.
20. Huang X, Huang Y, Yang Y, Wei S, Qin Q*. Involvement of fish signal transducer and activator of transcription 3 (STAT3) in SGIV replication and virus induced paraptosis. Fish Shellfish Immunol. 2014; 41(2): 308-16.