但学明
但学明简介
一、个人信息
姓名:但学明
职务:水生动物医学系主任
职称:教授
联系方式:dxm72@scau.edu.cn
个人简介:
男,博导,美国康奈尔大学访问学者,广东省现代农业产业体系岗位专家,海洋学院水生动物医学系主任。长期从事水产动物免疫学及病害防控研究,近年来主要围绕对我国海水养殖业造成严重危害的刺激隐核虫病开展免疫防控研究。近年来主持2项国家基金面上项目和8项省部级项目,第一作者或通讯作者发表SCI论文47篇,获得授权专利7项,荣获广东省科学技术二等奖1项,校级教学一等奖和二等奖各1项,指导研究生获得国家奖学金3人次,省级优秀研究生3人次,校级优秀毕业研究生6人次,校级优秀研究生学位论文7篇。
二、第一作者或通讯作者发表的论文
1.但学明,张耀光,谢小军.南方鲇鳃的光镜和扫描电镜观察. 西南师范大学学报(自然科学版). 1999,24(6):666-673
2.但学明,林小涛,方彰胜,王昀.暗纹东方鲀小规格鱼种池塘培育试验.水利渔业,2004,24(2):47-48
3.但学明,林小涛.广东地区人工养殖暗纹东方鲀毒性检测.水利渔业,2005,2(4):9-12
4.Xue-Ming Dan, A.X.Li, X.Q.Zhu. A standardized method to propagate Cryptocaryon irritans on a susceptible host pompano Trachinotus ovatus. Aquaculture, 2006, 258:127-133.
5.但学明,李安兴,林小涛,柏建山.卵形鲳鲹对刺激隐核虫的免疫应答和免疫保护研究.水生生物学.2008.32(1):12-17
6.Xue-Ming Dan, X.T. Lin, Y.X. Yan, N. Teng, Z.L.Tan, A.X. Li. A technique for the preservation of Cryptocaryon irritans at low temperatures. Aquaculture, 2009, 297:112–115.
7.Xue-Ming Dan, Zhang TW, Li YW, Li AX*. Immune responses and immune-related gene expression profile in orange-spotted grouper after immunization with Cryptocaryon irritans vaccine. Fish and Shellfish Immunology, 2013, 34(3):885-891.
8.Xue-Ming Dan, Zhong ZP, Li YW, Luo XC, Li AX*. Cloning and expression analysis of grouper (Epinephelus coioides) M-CSFR gene post Cryptocaryon irritans infection and distribution of M-CSFRt cells. Fish and Shellfish Immunology, 2013, 35(3): 240-248.
9.Ruijun Li, Anxing Li, Xue-Ming Dan(通讯作者), Siganus oramin recombinant L-amino acid oxidase is lethal to Cryptocaryon irritans. Fish and Shellfish Immunology, 2013, 35 (6):1867-1873.
10.但学明,刘丽,孙媛,甘炼*。以执业兽医资格考试为导向的水产动物疾病学教学改革初探。中国兽医杂志,2014,50(3):99-101
11.Xue-Ming Dan, Guan-Jie Yan, An-JieZhang, Zhen-Dong Cao, Shi-Jian Fu*. Effects of stable and diel-cycling hypoxia on hypoxia tolerance, postprandial metabolic response, and growth performance in juvenile qingbo (Spinibarbus sinensis). Aquaculture, 2014, 428-429(5): 21-28.
12.Xiang Zhang, Yan-Wei Li,Ze-Quan Mo, Xiao-Chun Luo,Hong-YanSun,Peng Liu,An-Xing Li,Su-Ming Zhou,Xue-Ming Dan(通讯作者).Outbreak of a novel disease associated with Vibrio mimicus infection in freshwater cultured yellow catfish, Pelteobagrus fulvidraco. Aquaculture, 2014, 432:119-124.
13.Ze-Quan Mo, Yan-Wei Li, Ling Zhou, An-Xing Li, Xiao-Chun Luo, Xue-Ming Dan(通讯作者). Grouper (Epinephelus coioides) IL-34/MCSF2 andMCSFR1/MCSFR2 were involved in mononuclear phagocytes activation against Cryptocaryon irritans infection. Fish and Shellfish Immunology, 2015, 43(1): 142-149.
14.Ze-Quan Mo, Ling Zhou, Xiang Zhang, Lian Gan, Li Liu, Xue-Ming Dan(通讯作者). Outbreak of Edwardsiella tarda infection in farm-cultured giant mottled eel Anguilla marmorata in China. Fisheries Science, 2015, 81:899–905.
15.Ze-Quan Mo, Yan-Wei Li, Ling Zhou, An-Xing Li, Xiao-Chun Luo, Xue-Ming Dan(通讯作者). Characterization and expression analysis of two novel CCR6 chemokine receptors and their three potential ligands CCL20Ls of grouper (Epinephelus coioides) post Cryptocaryon irritans infection. Fish and Shellfish Immunology, 2015, 47 (1): 280-288.
16.Zhou L.L., Dan X.M.(并列第一作者), Li Y.W., Li X.X., Chen X.L,Li Y, Gan Gan L. Effect of reducing 3.2% dietary protein level on the growth performance and immunity of Nile tilapia (Oreochromis niloticus) with supplementation of multi amino acids. Iranian Journal of Fisheries Sciences, 2015, 14(4) 997-1009.
17.Yan-Wei Li, Dong-Dong Xu, Xia Li, Ze-Quan Mo, Xiao-Chun Luo, An-Xing Li, Xue-Ming Dan(通讯作者). Identification and characterization of three TLR1 subfamily members from the orange-spotted grouper, Epinephelus coioides. Developmental and Comparative Immunology, 2016, 61:180-189.
18.Yan-Wei Li, Fei Zhao, Ze-Quan Mo, Xiao-Chun Luo, An-Xing Li, Xue-Ming Dan(通讯作者).Characterization, expression, and functional study of IRAK-1 from grouper, Epinephelus coioides. Fish and Shellfish Immunology, 2016, 56: 374-381.
19.Ze-Quan Mo, Man Yang, Hai-Qing Wang, Yang Xu, Mian-Zhi Huang, Guo-Feng Lao, Yan-Wei Li, An-Xing Li, Xiao-Chun Luo, Xue-Ming Dan(通讯作者). Grouper (Epinephelus Coioides) Bcr Signaling Pathway Was Involved in Response against Cryptocaryon Irritans Infection. Fish and Shellfish Immunology, 2016, 57:198-205.
20.Ze-Quan Mo, Yan-Wei Li, Hai-Qing Wang, Jiu-Le Wang, Lu-Yun Ni, Man Yang, Guo-Feng Lao,Xiao-Chun Luo, An-Xing Li, Xue-Ming Dan(通讯作者). Comparative transcriptional profile of the fish parasite Cryptocaryon irritans. Parasites and Vectors. 2016, 9:630.
21.Man Yan, Ling Zhou, Hai-Qing Wang,Xiao-Chun Luo, Xue-Ming Dan(通讯作者),Yan-Wei Li. Molecular cloning and expression analysis of CCL25 and its receptor CCR9s from Epinephelus coioides post Cryptocaryon irritans infection. Fish and Shellfish Immunology, 2017, 67:402-410.
22.Lu-Yun Ni,Ling Zhou,Hai-Qing Wang,Xiao-Chun Luo, Xue-Ming Dan(通讯作者),Yan-Wei Li. Identification and expression analysis of three XCR1-like receptors from Epinephelus coioides after Cryptocaryon irritans infection. Fish and Shellfish Immunology, 2017, 67:95-102.
23.Ze-Xiang Li,Yan-Wei Li, Shun Xu,Yang Xu, Ze-Quan Mo, Xue-Ming Dan(通讯作者),Xiao-Chun Luo. Grouper (Epinephelus coioides) TCR signaling pathway was involved in response against Cryptocaryon irritans infection. Fish and Shellfish Immunology, 2017, 64:176-184.
24.Ze-Quan Mo, Jiu-Le Wang,Man Yan,Lu-Yun Ni,Hai-Qing Wang,Guo-Feng Lao,Yan-Wei Li,An-Xing Li,Xiao-Chun Luo, Xue-Ming Dan(通讯作者).Characterization and expression analysis of grouper (Epinephelus coioides) co-stimulatory molecules CD83 and CD80/86 post Cryptocaryon irritans infection .Fish and Shellfish Immunology, 2017, 67:467-474.
25.Hong-Yan Sun, Mian-Zhi Huang, Yan-Wei Li, Jia-Hao Huang, Ze-Quan Mo, Rui-Ai Chen , Xue-Ming Dan(通讯作者). Two novel p38 MAPKs identified from Epinephelus coioides and their expression pattern in response to Cryptocaryon irritans infection. Fish and Shellfish Immunology, 2017, 67:459-466.
26.Jiu-Le Wang, Guo-Feng Lao, Yan-Wei Li, Man Yang, Ze-Quan Mo, Xue-Ming Dan(通讯作者).Effects of temperature and host species on the life cycle of Cryptocaryon irritans. Aquaculture, 2018, 485: 49–52.
27.Hong-Yan Sun, Mian-Zhi Huang, Ze-Quan Mo, Liang-Shi Chen, Guo Chen, Man Yang, Lu-Yun Ni, Yan-Wei Li, Xue-Ming Dan(通讯作者). Characterization and expression patterns of ERK1 and ERK2 from Epinephelus coioides against Cryptocaryon irritans infection. Fish and Shellfish Immunology, 2018, 74: 393-400.
28.Wang HQ, Zhou L, Yang M, Luo XC, Li YW, Xue-Ming Dan(通讯作者). Identification and characterization of myeloperoxidase in orange-spotted grouper (Epinephelus coioides). Fish and Shellfish Immunology , 2018,72:230-236.
29.Ze-Quan Mo, Qing Han, Yu-Long Zeng, Jiu-Le Wang, Xue-Zhu Li, Yan-Wei Li,Hong-Yan Sun, An-Xing Li, Xiao-Chun Luo, Xue-Ming Dan(通讯作者). Molecular characterization and function analysis of grouper (Epinephelus coioides) Bruton's tyrosine kinase BTK. Fish and Shellfish Immunology, 2018,77:91-99.
30.Hong-Yan Sun, Xin-Hui Cao, Yu-Feng Jiang, Lu-Yun Ni, Ze-Quan Mo, Qi-wei Qin,Yan-Wei Li, Xue-Ming Dan(通讯作者). Outbreak of a novel disease associated with Citrobacter freundii infection in freshwater cultured Stingray. Aquaculture, 2018, 492:35-39.
31.Song Guo, Zequan Mo, Zheng Wang, Jun Xu, Yanwei Li, Xue-Ming Dan(通讯作者), Anxing Li. Isolation and Pathogenicity of Streptococcus iniae in cage-cultured Trachinotus ovatus in China. Aquaculture, 2018,492:247-252.
32.Ze-Quan Mo, Jiu-Le Wang, Rui Han, Qing Han, Yan-Wei Li, Hong-Yan Sun,Xiao-Chun Luob, Xue-Ming Dan(通讯作者). Identification and functional analysis of grouper (Epinephelus coioides) B-cell linker protein BLNK. Fish and Shellfish Immunology, 2018, 81:399-407.
33.Ze-Quan Mo, Shun Xu, Donna M. Cassidy-Hanley, Yan-Wei Li, Daniel Kolbin,Jennifer M. Fricke, An-Xing Li, Theodore G. Clark, Xue-Ming Dan(通讯作者). Characterization and immune regulation role of an immobilization antigen from Cryptocaryon irritans on groupers, Scientific Reports, 2019, 9:1029.
34.Ze-Quan Mo, Rui Han, Jiu-Le Wang, Lu-Yun Ni, Yu-Ling Su, Xue-Li Lai, Zhi-Chang He,Hong-Ping Chen, Yan-Wei Li, Hong-Yan Sun, Xiao-Chun Luo, Xue-Ming Dan(通讯作者). Characterization and functional analysis of grouper (Epinephelus coioides) MEK1 and MEK2. Fish and Shellfish Immunology, 2019, 84: 1090-1097.
35.Yang M, Han R, Ni LY, Luo XC, Li AX, Dan XM(通讯作者),Li YW.Molecular characteristics and functional study of tumor necrosis factor receptor-associated factor 2 from the orange-spotted grouper (Epinephelus coioides).Fish and Shellfish Immunology, 2019, 84:726-32.
36.Yang M , Han R, Ni LY,Luo XC, Li AX, Dan XM(通讯作者), Tsim KWK, Li YW. Molecular characteristics and function study of TNF receptor-associated factor 5 from grouper (Epinephelus coioides) . Fish and Shellfish Immunology, 2019, 87: 730-736.
37. Su, Yu Lin; Chen, Guo; Chen, Liang Shi; Li, Jia Zhou; Wang, Gang; He, Jia Yang; Zhan, Tian Yong; Li, Yan Wei; Yan, Mu Ting; Huang, You Hua; Qin, Qi Wei; Dan, Xue Ming(通讯作者); Sun, Hong Yan. Effects of antimicrobial peptides on serum biochemical parameters, antioxidant activity and non-specific immune responses in Epinephelus coioides. Fish and Shellfish Immunology, 2019, 86: 1081-1087.
38.Han, Ru; Zeng, Yu long; Ni, Lu Yun; Luo, Xiao Chun; Li, An Xing; Dan, Xue Ming(通讯作者); Li, Yan Wei. Grouper (Epinephelus coioides) MyD88 adaptor-like (Mal): Molecular cloning, expression, and functionality. Fish and Shellfish Immunology, 2019, 93: 308-312.
39.Ni, Lu Yun; Han, Qing; Chen, Hong Ping; Luo, Xiao Chun; Li, An Xing; Dan, Xue Ming(通讯作者); Li, Yan Wei. Grouper (Epinephelus coioides) Mpeg1s: Molecular identification, expression analysis, and antimicrobial activity. Fish and Shellfish Immunology, 2019, 92: 690-697.
40.Ze-Quan Mo, Xue-Li Lai, Wan-Tao Wang, Hong-Ping Chen, Zhi-Chang Hea, Rui Han,Jiu-Le Wang, Xiao-Chun Luo, Yan-Wei Li, Xue-Ming Dan(通讯作者). Identification and characterization of c-raf from orange-spotted grouper. Fish and Shellfish Immunology, 2020, 96:311-318.
41.Jun-Jin Deng,Shun Xu,Yan-Wei Li,Dong-Dong Xu,Ze-Quan Mo,Jia-Zhou Li,Xue-Ming Dan(通讯作者),Xiao-Chun Luo. Role of major histocompatibility complex II antigen-presentation pathway genes in orange-spotted grouper infected with Cryptocaryon irritans. Journal of Fish Diseases, 2020, 43(12): 1541-1552.
42.Rui Han, Jiule Wang, Hongping Chen, Xiaochun Luo, Anxing Li, Xueming Dan(通讯作者),Yanwei Li. Grouper (Epinephelus coioides) IRAK-4 regulates activation of NF-κB and expression of inflammatory cytokines in grouper spleen cells. Fish and Shellfish Immunology, 2020, 106: 938-947.
43.Rui Han, Jiu-Le Wang, Hong-Ping Chen, Xiao-Chun Luo, An-Xing Li, Xue-Ming(通讯作者)Dan,Yan-Wei Li. IκB kinase α-1 and -2 regulate cytokine expression in the orange-spotted grouper (Epinephelus coioides). Fish and Shellfish Immunology, 2020, 101: 291-301.
44.Lu-Yun Ni, Hong-Ping Chen, Rui Han, Xiao-Chun Luo, An-Xing Li, Jia-Zhou Li,Xue-Ming Dan(通讯作者), Yan-Wei Li. Distribution of Mpeg1+ cells in healthy grouper (Epinephelus coioides) and after Cryptocaryon irritans infection. Fish and Shellfish Immunology, 2020, 104: 222-227.
45.Jiu-Le Wang, Hai-Qing Wang, Ze-Quan Mo, Ling Zhou, Xiao-Chun Luo, An-Xing Li,Yan-Wei Li, Xue-Ming Dan(通讯作者). Orange-spotted grouper (Epinephelus coioides) NADPH oxidase: Cloning and expression analysis after Cryptocaryon irritans infection. Fish and Shellfish Immunology, 2020, 99: 291-300.
46.Zijun Lu , Ren Gao, Yafei Duan,Rui Han,Wenjie Guo,Xueming Dan(通讯作者),Yanwei Li. Isolation and genetic characterization of Flavobacterium columnare from grass carp, Ctenopharyngodon idellus, in China. Aquaculture, 2021, 541:1-8.
47.Yanwei Li,Biao Jiang,Zequan Mo,Anxing Li,Xueming Dan. Cryptocaryon irritans (Brown, 1951) is a serious threat to aquaculture of marine fish. Reviews in Aquaculture,2021,
三、参与发表的论文
1.Bai, JS (Bai, Jian-Shan); Xie, MQ (Xie, Ming-Quan); Zhu, XQ (Zhu, Xing-Quan); Dan, XM (Dan, Xue-Ming); Li, AX (Li, An-Xing). Comparative studies on the immunogenicity of theronts, tomonts and trophonts of Cryptocaryon irritans in grouper. PARASITOLOGY RESEARCH, 2008,102(2): 307-313.
2.Li, YW (Li, Yan-Wei); Luo, XC (Luo, Xiao-Chun); Dan, XM (Dan, Xue-Ming); Huang, XZ (Huang, Xia-Zi); Qiao, W (Qiao, Wei); Zhong, ZP (Zhong, Zheng-Ping); Li, AX (Li, An-Xing). Orange-spotted grouper (Epinephelus coioides) TLR2, MyD88 and IL-1 beta involved in anti-Cryptocaryon irritans response. Fish and Shellfish Immunology, 2011, 30(6): 1230-1240.
3.Li, YW (Li, Y. W.); Dan, XM (Dan, X. M.); Zhang, TW (Zhang, T. W.); Luo, XC (Luo, X. C.); Li, AX (Li, A. X.). Immune-related genes expression profile in orange-spotted grouper during exposure to Cryptocaryon irritans. PARASITE IMMUNOLOGY, 2011, 33(12): 679-687.
4.Li, YW (Li, Yan-Wei); Luo, XC (Luo, Xiao-Chun); Dan, XM (Dan, Xue-Ming); Qiao, W (Qiao, Wei); Huang, XZ (Huang, Xia-Zi); Li, AX (Li, An-Xing). Molecular cloning of orange-spotted grouper (Epinephelus coioides) TLR21 and expression analysis post Cryptocaryon irritans infection. Fish and Shellfish Immunology, 2012, 32(3): 476-481.
5.Yin, F (Yin, Fei); Dan, XM (Dan, Xue-Ming); Sun, P (Sun, Peng); Shi, ZH (Shi, Zhao-Hong); Gao, QX (Gao, Quan-Xin); Peng, SM (Peng, Shi-Ming); Li, AX (Li, An-Xing). Growth, feed intake and immune responses of orange-spotted grouper (Epinephelus coioides) exposed to low infectious doses of ectoparasite (Cryptocaryon irritans). Fish and Shellfish Immunology, 2014, 36(1): 291-298.
6.Yin, F (Yin, Fei); Gong, QY (Gong, Qiyang); Li, YW (Li, Yanwei); Dan, XM (Dan, Xueming); Sun, P (Sun, Peng); Gao, QX (Gao, Quanxin); Shi, ZH (Shi, Zhaohong); Peng, SM (Peng, Shiming); Li, AX (Li, Anxing). Effects of Cryptocaryon irritans infection on the survival, feeding, respiratory rate and ionic regulation of the marbled rock fish Sebastiscus marmoratus. PARASITOLOGY, 2014,141(2): 279-286.
7.Li, YW (Li, Yan-Wei); Li, X (Li, Xia); Xiao, XX (Xiao, Xi-Xi); Zhao, F (Zhao, Fei); Luo, XC (Luo, Xiao-Chun); Dan, XM (Dan, Xue-Ming); Li, AX (Li, An-Xing). Molecular characterization and functional analysis of TRAF6 in orange-spotted grouper (Epinephelus coioides). DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2014,44(1): 217-225.
8.Li, YW (Li, Yan-Wei); Mo, XB (Mo, Xu-Bing); Zhou, L (Zhou, Ling); Li, X (Li, Xia); Dan, XM (Dan, Xue-Ming); Luo, XC (Luo, Xiao-Chun); Li, AX (Li, An-Xing). Identification of IRAK-4 in grouper (Epinephelus coioides) that impairs MyD88-dependent NF-kappa B activation. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2014,45(1): 190-197.
9.Huang, XZ (Huang, Xia-Zi); Li, YW (Li, Yan-Wei); Mai, YZ (Mai, Yong-Zhan); Luo, XC (Luo, Xiao-Chun); Dan, XM (Dan, Xue-Ming); Li, AX (Li, An-Xing). Molecular cloning of NCCRP-1 gene from orange-spotted grouper (Epinephelus coioides) and characterization of NCCRP-1(+) cells post Cryptocaryon irritans infection. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2014, 46(2): 267-278.
10.Li, YW (Li, Yan-Wei); Wang, Z (Wang, Zheng); Mo, ZQ (Mo, Ze-Quan); Li, X (Li, Xia); Luo, XC (Luo, Xiao-Chun); Dan, XM (Dan, Xue-Ming); Li, AX (Li, An-Xing). Grouper (Epinephelus coioides) MyD88 and Tollip: Intracellular localization and signal transduction function. Fish and Shellfish Immunology, 2015,42(1): 153-158.
11.Sun, HY (Sun, Hongyan); Dong, JD (Dong, Junde); Ren, CH (Ren, Chunhua); Zhang, LP (Zhang, Lvping); Dan, XM (Dan, Xueming); Chen, C (Chen, Chang); Zhang, YZ (Zhang, Yuanzhou); Hu, CQ (Hu, Chaoqun). Cloning and differential expression of Na,K-ATPase in Penaeus vannamei. MARINE BIOLOGY RESEARCH, 2015,11(9): 983-989.
12.Li, YW (Li, Y. W.); Li, X (Li, X.); Wang, Z (Wang, Z.); Mo, ZQ (Mo, Z. Q.); Dan, XM (Dan, X. M.); Luo, XC (Luo, X. C.); Li, AX (Li, A. X.). Orange-spotted grouper Epinephelus coioides Tak1: molecular identification, expression analysis and functional study. JOURNAL OF FISH BIOLOGY, 2015, 86: 417-430.
13.Yin, F (Yin, Fei); Sun, P (Sun, Peng); Tang, BJ (Tang, Baojun); Dan, XM (Dan, Xueming); Li, AX (Li, Anxing). Immunological, ionic and biochemical responses in blood serum of the marine fish Trachinotus ovatus to poly-infection by Cryptocaryon irritans. EXPERIMENTAL PARASITOLOGY, 2015, 154: 113-117.
14.Jiang, B (Jiang, B.); Li, YW (Li, Y. W.); Abdullahi, AY (Abdullahi, A. Y.); Dan, XM (Dan, X. M.); Gong, H (Gong, H.); Ke, QZ (Ke, Q. Z.); Li, AX (Li, A. X.); Li, GQ (Li, G. Q.). Placemat and rotational culturing: A novel method to control Cryptocaryon irritans infection by removing tomonts. AQUACULTURE, 2016,459: 84-88.
15.Gan, L (Gan, Lian); Li, XX (Li, Xiao-xia); Zhou, LL (Zhou, Li Liu); Zhu, SX (Zhu, Shao Xuan); Dan, XM (Dan, Xue Ming); Liu, L (Liu, Li); Tang, HJ (Tang, Hui-Juan); Li, GF (Li, Gui Feng); Wang, GJ (Wang, Guang Jun). Effects of Different Lipid Sources on the Growth Performance and Muscle Fatty Acid Composition of Juvenile Anguilla marmorata. ISRAELI JOURNAL OF AQUACULTURE-BAMIDGEH, 2017, 69:213-218.
16.Bai, JS (Bai, Jian-Shan); Li, YW (Li, Yan-Wei); Deng, Y (Deng, Yan); Huang, YQ (Huang, Yan-Qiong); He, SH (He, Shu-Hua); Dai, J (Dai, Jin); Zhao, SZ (Zhao, Shang-Zhi); Dan, XM (Dan, Xue-Ming); Luo, XC (Luo, Xiao-Chun). Molecular identification and expression analysis of TLR5M and TLR5S from orange-spotted grouper (Epinepheluscoioides). Fish and Shellfish Immunology, 2017, 63:97-102.
17.Su, Yu-Ling; Chen, Jin-Peng; Mo, Ze-Quan; Zheng, Jia-Ying; Lv, Shun-You; Li, Pin-Hong; Wei, Yu-Si; Liang, Yu-Lin; Wang, Shao-Wen; Yang, Min; Dan, Xue-Ming; Huang, Xiao-Hong; Huang, You-Hua; Qin, Qi-Wei; Sun, Hong-Yan.A novel MKK gene (EcMKK6) in Epinephelus coioides: Identification, characterization and its response to Vibrio alginolyticus and SGIV infection.Fish and Shellfish Immunology,2019, 92:500-507.
18.Hu, Ya Zhou; Li, Xia; Han, Rui; Jiang, Biao; Li, Yan Wei; Dan, Xue Ming; Li, An Xing*. Molecular identification and expression analysis of TAB1 from orange-spotted grouper (Epinephelus coioides). Developmental and Comparative Immunology, 2019, 90: 152-156.
19.李言伟,江飚,但学明,李安兴.鱼类抗刺激隐核虫感染的黏膜免疫研究进展.水产学报, 2019: 156-167.
四、主持和参加的项目
项目名称 | 项目类别 | 排名情况 | 到位经费 (万元) | 研究期限 |
刺激隐核虫分子抗原诱发石斑鱼的保护性免疫及其机制41976081 | 国家自然科学基金项目 | 参加 | 72 | 2020-01-01--2023-12-31 |
不同免疫模式下刺激隐核虫诱导的石斑鱼IgM和IgT应答特性41876162 | 国家自然科学基金项目 | 主持 | 72 | 2019-01-01--2022-12-31 |
2019年广东省水产品质量安全风险评估项目 | 广东省农业厅招标项目 | 主持 | 100 | 2019-09-09--2020-12-31 |
近岸海区刺激隐核虫病预警(2019年) | 广东省海洋渔业科技推广专项 | 主持 | 18 | 2019-8-1— 2019.12.31 |
广东省水产疫病监测与综合防控共性关键技术研发创新团队 | 广东省现代农业产业共性关键技术研发创新团队 | 主持 | 7 | 2019-05-28--2020-11-30 |
石斑鱼IRAK-4负调控MyD88信号转导功能的机制 | 广东省自然科学基金 | 参加 | 10 | 2018-11-03--2021-04-30 |
草鱼和罗非鱼免疫防病技术的试验及推广应用SDYY-2018-03 | 省级促进经济发展专项(现代渔业发展用途) | 主持 | 200 | 2018-05-01--2019-05-01 |
刺激隐核虫免疫诱导的石斑鱼抗体应答研究 | 珠江新星 | 参加 | 30 | 2018-04-01--2021-03-31 |
广东省南美白对虾种业现状调查及分析 | 广东省海洋渔业科技推广专项 | 参加 | 14 | 2018-08-13--2018-12-28 |
海水养殖鱼类重要疫病新型高效疫苗的研发生产及推广应用2018C001 | 省级促进经济发展专项(海洋经济发展用途) | 主持 | 80 | 2018-05-01--2020-04-30 |
近岸海区刺激隐核虫病预警 | 广东省海洋与渔业财政专项资金项目 | 主持 | 5 | 2018-05-01--2019-04-30 |
北部湾海区刺激隐核虫病监测与预警 | 广东省海洋与渔业财政专项资金项目 | 主持 | 10 | 2017-11-01--2018-10-31 |
名优水产繁育及健康养殖技术示范 | 广东省中央财政农业技术推广项目 | 参加 | 30 | 2017-10-01--2019-12-31 |
近岸海区刺激隐核虫病调查与预警 | 广东省海洋与渔业财政专项资金项目 | 主持 | 9 | 2017-06-01--2018-06-29 |
鱼源拟态弧菌流行病学调查与免疫防控技术研究 | 广东省海洋与渔业财政专项资金项目 | 参加 | 50 | 2017-02-21--2019-08-01 |
广东重点养殖区域气单胞菌耐药性调查 | 广东省海洋与渔业财政专项资金项目 | 参加 | 7.5 | 2016-10-08--2018-06-30 |
石斑鱼蚂蟥病的生态防控研究及示范推广 | 广东省海洋与渔业财政专项资金项目 | 参加 | 10 | 2016-10-01--2018-12-31 |
广东省进口水产种苗主导品种生产现状调查及管理对策 | 广东省海洋与渔业财政专项资金项目 | 主持 | 15 | 2016-08-01--2017-05-31 |
重大疫病监测与水产苗种产地检疫 | 广东省海洋与渔业财政专项资金项目 | 主持 | 5 | 2016-04-18--2016-12-31 |
刺激隐核虫病的免疫防控试验 | 广东省海洋与渔业财政专项资金项目 | 参加 | 80 | 2016-04-15--2017-04-30 |
抗刺激隐核虫化学药物的筛选及应用 | 横向项目 | 主持 | 15 | 2015-09-15--2017-09-15 |
基于转录组学的刺激隐核虫保护性抗原基因的筛选及其在四膜虫上的表达和应用A201501B11 | 广东省海洋渔业科技推广专项 | 主持 | 40 | 2015-03-12--2016-12-31 |
重大水生物疫病专项监测项目(2015) | 广东省海洋与渔业财政专项资金项目 | 主持 | 10 | 2015-03-03--2016-06-30 |
刺激隐核虫重组亚单位疫苗候选基因的筛选及其在四膜虫的表达和应用 | 广东省海洋与渔业财政专项资金项目 | 主持 | 20 | 2014-11-20--2015-12-31 |
篮子鱼血清中抗刺激隐核虫活性物质的他离鉴定及初步应用 | 广东省海洋与渔业财政专项资金项目 | 主持 | 20 | 2014-05-10--2015-11-10 |
重大水生动物疫病专项监测项目 | 广东省海洋与渔业财政专项资金项目 | 主持 | 10 | 2013-06-10--2014-04-30 |
花鳗鲡苗种培育和健康养殖关键技术的研究 | 广东省海洋渔业科技推广专项 | 主持 | 100 | 2012-10-30--2014-05-31 |
基于四膜虫表达体系的刺激隐核虫保护性抗原的筛选和鉴定31272681 | 国家自然科学基金项目 | 参加 | 27 | 2012-09-12--2016-12-31 |
篮子鱼抗刺激隐核虫感染机制的研究S2012010009148 | 广东省自然科学基金 | 主持 | 5 | 2012-08-16--2014-10-01 |
黄斑蓝子鱼对刺激隐核虫的天然抗性机制研究31172443 | 国家自然科学基金项目 | 主持 | 60 | 2011-08-16--2015-12-31 |
刺激隐核虫感染诱发的海水鱼类粘膜免疫反应研究30871934 | 国家自然科学基金项目 | 参加 | 10.5 | 2008-08-20--2011-12-31 |
海水养殖鱼类刺激隐核虫病防治关键技术研究与应用2007B080701009 | 广东省科技攻关项目 | 参加 | 30 | 2007-10-24--2008-12-01 |
五、授权专利
1.一种刺激隐核虫的标准化传代增殖方法及其专用收集器,专利号ZL200610035575.2,排名第2
2.一种双色鳗幼鳗阶段粉状配合饲料,专利号ZL201410460183.5,排名第2
3.一种刺激隐核虫局部感染斜带石斑鱼鳃组织的免疫模型构建方法,专利号ZL201810346051.8,排名第2
4.一种刺激隐核虫局部感染斜带石斑鱼皮肤的免疫模型构建方法,专利号ZL201810345955.9,排名第2
5.一种斜带石斑鱼CCR12的基因克隆和原核表达、纯化方法,专利号ZL 201710333645.0,排名第1
6.一种斜带石斑鱼CCR12的多克隆抗体制备方法及其应用,专利号ZL 201710333721.8,排名第1
7.一种刺激隐核虫亚单位疫苗的制备方法及其应用,专利号ZL201710505968.3,排名第1
六、奖励和荣誉
1.成果鉴定证书,刺激隐核虫生物学及综合防控技术研究,2013.4.23,广州,排名第三
2.2014年广东省科学技术二等奖,“刺激隐核虫生物学及综合防控技术研究”,证书号:粤府证[2014]1417号,项目编号:B02-2-2-02-R03;
3.2015年华南农业大学动物科学学院优秀班主任;
4.2015年华南农业大学动物科学学院优秀共产党员;
5.校级教学成果一等奖,“两联动两融合”水产类新型人才培养的探索与实践,证书编号:JXCG21014
6.校级教学成果二等奖,研究生“水产养殖技术”课程的“学研产“教学模式,证书编号:JXCG21086
七、研究生招收专业及方向
1. 博士研究生(理学)
(1)水生生物学专业/水生动物免疫与病害防控方向
2. 全日制学术型硕士研究生
(1)水生生物学专业/水生动物免疫与病害防控方向(理学)
(2)水产养殖学专业/水产医学方向(农学)
3. 全日制专业学位硕士研究生(农学)
(1)渔业发展专业/水生动物疫病防控方向(农学)
八、培养研究生情况
毕业研究生16名,在读博士生4名,在读硕士生6名,研究生获得以下荣誉:
1.国家奖学金:莫泽权(2015年),倪露芸(2017年),莫泽权(2018年,博士)
2.省级优秀毕业研究生:莫泽权(2016年),杨曼(2018年), 莫泽权(2019年,博士)
3.校级优秀毕业研究生:莫泽权(2016年),杨曼(2018年),王久乐(2018年),倪露芸(2019年),莫泽权(2019年,博士)
4.校级优秀研究生学位论文:莫泽权(2016年),王海青(2017年),杨曼(2018年),王久乐(2018年),倪露芸(2019年),莫泽权(2019年,博士)
九、讲授课程情况
1. 本科生课程
《水产动物疾病学》,《水产动物病理学》,《水产动物组织胚胎学》
2. 研究生课程
《水产动物免疫与病害防控学》