Current Position：
首页 Faculty Professors
Huang Xiaohong
Personal profile:
Huang Xiaohong: Female, Henan Anyang, Ph.D., researcher. Research direction: Cell and molecular mechanism of pathogenicity of marine fish virus infection. In recent years, he has presided over 4national-level projects , including the 863 project, the National Natural Science Foundation of China and the 973 sub-project; the first author or correspondent author (including the common first and co-author) published 23SCI papers ; Authorized 3 patents ; participated in the preparation of 2 monographs .
work experience:
2015.05-2016.05 National University of Singapore Visiting Scholar
2014.12- present Researcher, South China Sea Institute of Oceanology, Chinese Academy of Sciences
2009.10-2014.12 Associate Research Fellow, South China Sea Institute of Oceanology, Chinese Academy of Sciences
2009.01-2009.10 Assistant Researcher, South China Sea Institute of Oceanology, Chinese Academy of Sciences
2006.10-2009.01 Sun Yat-sen University Postdoctoral
Education experience:
2001.09-2006.07 Aquatic Biology, Institute of Hydrobiology, Chinese Academy of Sciences
1997.09-2001.07 Freshwater fishery of Henan Normal University
Research projects:
1 . 863 project , 2014AA093507 , research and development of marine virus main virus and bacterial pathogen subunit vaccine, 2014.1-2015.12 , 195 , ongoing research, host.
2 . National Natural Science Foundation of China, 31372566 , Grouper ubiquitin proteasome system to regulate the replication of iridovirus SGIV infection, 2014.1-2017.12 , 780,000 , under research, host.
3 . National Natural Science Foundation of China, 31172445 , using fluorescent-labeled recombinant virus to study the motility of grouper iridescent virus infection and screening of antiviral drugs, 2012.1-2015.12 , 620,000 , completion , and host.
4．973子课题，2012CB114406、鱼类疫病免疫防治的系统疫苗学原理与技术途径、2012.1-2016.12、57.1万、结题、主持。
发表论文：
1. Yang Y, Huang Y, Yu Y, Zhou S, Wang S, Yang M, Qin Q, Huang X*. Negative regulation of the innate antiviral immune response by TRIM62 from orange spotted grouper. Fish Shellfish Immunol. 2016, 57:68-78.
2. Yang Y, Huang Y, Yu Y, Yang M, Zhou S, Qin Q, Huang X*.RING domain is essential for the antiviral activity of TRIM25 from orange spotted grouper. Fish Shellfish Immunol. 2016, 55:304-14.
3. Wang W, Huang Y, Yu Y, Yang Y, Xu M, Chen X, Ni S, Qin Q, Huang X*. Fish TRIM39 regulates cell cycle progression and exerts its antiviral function against iridovirus and nodavirus. Fish Shellfish Immunol. 2016,50:1-10.
4. Yu Y, Huang Y, Wei S, Li P, Zhou L, Ni S, Huang X**, Qin Q*.A tumour necrosis factor receptor-like protein encoded by Singapore grouper iridovirus modulates cell proliferation, apoptosis and viral replication.J Gen Virol. 2016,97(3):756-66.
5. Huang Y, Yu Y, Yang Y, Yang M, Zhou L, Huang X**, Qin Q*. Fish TRIM8 exerts antiviral roles through regulation of the proinflammatory factors and interferon signaling. Fish Shellfish Immunol. 2016, 54:435-44.
6. Huang Y, Yang M, Yu Y, Yang Y, Zhou L, Huang X**, Qin Q*. Grouper TRIM13 exerts negative regulation of antiviral immune response against nodavirus. Fish Shellfish Immunol. 2016, 55:106-15.
7. Huang Y, Yu Y, Yang Y, Yang M, Zhou L, Huang X**, Qin Q*. Antiviral function of grouper MDA5 against iridovirus and nodavirus. Fish Shellfish Immunol. 2016,54:188-96.
8. Yu Y, Huang Y, Yang Y, Wang S, Yang M, Huang X**, Qin Q*. Negative regulation of the antiviral response by grouper LGP2 against fish viruses. Fish Shellfish Immunol. 2016, 56:358-66.
9. Huang XH, Huang YH, Xu L, Wei SN, Ouyang ZL, Feng J, Qin QW. Identification and characterizaiton of a novel lymphocystis disease virus isolate from cultured grouper in China. J Fish Dis. 2015, 38(4):379-87.
10. Huang Y, Ouyang Z, Wang W, Yu Y, Li P, Zhou S, Wei S, Wei J, Huang X**, Qin Q*. Antiviral role of grouper STING against iridovirus infection. Fish Shellfish Immunol. 2015, 47(1):157-67.
11. Guo CY, Huang YH, Wei SN, Ouyang ZL, Yan Y, Huang XH**, Qin QW**. Establishment of a new cell line from the heart of giant grouper, Epinephelus lanceolatus (Bloch), and its application in toxicology and virus susceptibility. J Fish Dis. 2015,38(2):175-86
12. Wei S, Huang Y, Huang X**, Qin Q*. Characterization of c-Jun from orange-spotted grouper, Epinephelus coioides involved in SGIV infection. Fish Shellfish Immunol. 2015, 43(1):230-40.
13. Huang X, Wang W, Huang Y, Xu L, Qin Q. Involvement of the PI3K and ERK signaling pathways in largemouth bass virus-induced apoptosis and viral replication. Fish Shellfish Immunol. 2014,41(2):371-9.
14. Huang X, Huang Y, Yang Y, Wei S, Qin Q. Involvement of fish signal transducer and activator of transcription 3 (STAT3) in SGIV replication and virus induced paraptosis. Fish Shellfish Immunol. 2014,41(2):308-16.
15. Wang S#, Huang X##, Huang Y, Hao X, Xu H, Cai M, Wang H, Qin Q.Entry of a novel marine DNA virus, Singapore grouper iridovirus, into host cells occurs via clathrin-mediated endocytosis and macropinocytosis in a pH-dependent manner. J Virol. 2014,88(22):13047-63.
16. Fu J, Huang Y, Cai J, Wei S, Ouyang Z, Ye F, Huang X**, Qin Q*. Identification and characterization of Rab7 from orange-spotted grouper, Epinephelus coioides. Fish Shellfish Immunol. 2014, 36(1):19-26.
17. Huang X, Huang Y, Cai J, Wei S, Ouyang Z, Qin Q. Molecular cloning, expression and functional analysis of ISG15 in orange-spotted grouper, Epinephelus coioides. Fish Shellfish Immunol. 2013, 34(5):1094-102.
18. Huang X, Huang Y, Cai J, Wei S, Gao R, Qin Q. Identification and characterization of a tumor necrosis factor receptor like protein encoded by Singapore grouper iridovirus. Virus Res. 2013,26;178(2):340-8.
19. Huang X, Gong J, Huang Y, Ouyang Z, Wang S, Chen X, Qin Q. Characterization of an envelope gene VP19 from Singapore grouper iridovirus. Virology Journal. 2013, 10: 354.
20. Cai J, Huang Y, Wei S, Ouyang Z, Huang X**, Qin Q*. Characterization of LPS-induced TNFα factor (LITAF) from orange-spotted grouper, Epinephelus coioides. Fish Shellfish Immunol. 2013, 5(6):1858-66.
21. Huang XH, Huang YH, Ouyang ZL, Qin QW. Establishment of a cell line from the brain of grouper (Epinephelus akaara) for cytotoxicity testing and virus pathogenesis. Aquaculture. 2011, 311:65-73
22. Huang X, Huang Y, Ouyang Z, Xu L, Yan Y, Cui H, Han X, Qin Q. Singapore grouper iridovirus, a large DNA virus, induces nonapoptotic cell death by a cell type dependent fashion and evokes ERK signaling. Apoptosis. 2011, 16(8):831-45.
23. Huang X, Huang Y, OuYang Z, Cai J, Yan Y, Qin Q. Roles of stress-activated protein kinases in the replication of Singapore grouper iridovirus and regulation of the inflammatory responses in grouper cells. J Gen Virol. 2011, 92(Pt 6):1292-301.
Publication of monographs and textbooks:
Participated in the compilation of Chen Songlin, Qin Qiwei, The Theory and Technology of Fish Cell Culture, Science Press, 2011 ; Wang Jianguo, Fish Diseases, China Agricultural Press, 2013.
